November 7, 2009



 

 Rotation Projects

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Program Faculty
Name of PI Title of Project

Adah Almutairi

Particulate immunotherapy: Polymeric nano-carriers engineered to target and respond to in vivo st

Timothy D. Bigby

Innate Immunity & Cyanide Toxicity

Rolf Bodmer

Genetic Models of Heart Disease

Gerry R. Boss

Reg. of Purine Synthesis by PI3K-Akt-mTOR Path/Devel of New Free Radical Drug

Philip E. Bourne

Pharmaceutical Sciences - Competitive Binding of Major Pharmaceuticals

Joan Heller Brown

GPCR signaling in cell growth and survival

Jack Bui

Tumor immunosurveillance

Nigel Calcutt

Diabetes and Neuropathy

John Carethers

The development of colorectal neoplasms

Steven D. Chessler

Cell-surface proteins in pancreatic beta cell function

Sara Courtneidge

Small molecule inhibitors of podosome/invadopodia formation

Shane Crotty

Long-term Humoral Immunity

Marcia Dawson

Chemical induced cardiogenesis and synthesis of ligands for orphan nuclear receptors

Antonio De Maio

Hsp70

Arshad Desai

Chromosome Segregation & Aneuploidy

Steven Dowdy

Regulation of G1 Cell Cycle Progression

Adam J. Engler

Fibronectin Matrix Induces Embryonic Stem Cell Differentiation

Jeffrey D. Esko

structure, biosynthesis, and function of glycoproteins and proteoglycans

Sylvia Evans

Building the Heart

Marilyn G. Farquhar

Novel G protein mediated signaling pathways in endocytosis, cell migration, and apoptosis

Gen-Sheng Feng

Molecular signaling mechanisms in stem cells and metabolic disorders

Susan Ferro-Novick

How organelles are inherited and how they maintain their identity in both yeast and mammals

Seth Field

Study the regulation of Golgi function by PtdIns(4)P and the PtdIns(4)P effector GOLPH3

Theodore Friedmann

Neurogenesis,induced pluripotent stem (iPS) cells & bioinformatics

Xiang-Dong Fu

RNA Splicing

Minoru Fukuda

The role of carbohydrates in tumor suppression

Frank Furnari

The role of PTEN tyrosine phosphorylation in brain tumor progression and resistance to treatment.

Richard Gallo

Antimicrobial Peptides & Molecular Regulation of the Injury Response

Mark H. Ginsberg

Integrin Signaling in Atherosclerosis

Christopher K. Glass

Nuclear receptor superfamily of transcription factors in macrophage

Joseph G. Gleeson

Neurosciences Lab

Steven Gonias

Protease receptors and their role in cancer, inflammation and nerve injury

John C. Guatelli

Modulation of the interferon-induced restriction factor BST-2 by the HIV-1 accessory protein Vpu

Bruce A. Hamilton

Neurogenetics, modifier genes, and mRNA export pathways

Dorit Hanein

NALP1 inflammasomes and inflammation signaling pathways

Stephen B. Howell

Cancer Pharmacology

Ziwei Huang

Structures and Interactions of Chemokine Receptors and Discovery of Novel Therapeutics

Yishi Jin

molecular and cellular mechanisms controlling the formation and function of the nervous system

Mark Kamps

Hox oncoproteins in hematopoietic stem cell differentiation & AML

Alexander S. Kauffman

Regulation of neuropeptide gene expression in the brain during puberty

Kenneth Kaushansky

Thrombopoietin (TPO) in regulating the growth and differentiation of megakaryocytes

Richard Klemke

Cell Migration and Cancer

Richard Kolodner

High throughput and cell biology analysis of the pathways that prevent genome instability

Fred Levine

Pancreatic Development

Robert C. Liddington

Engineering therapeutic antibodies and vaccine antigen candidates targeting membrane fusion prote

Jonathan H. Lin

Protein Misfolding

Stuart Lipton

Neurogenesis

J. Andrew McCammon

Computer‐aided Drug Discovery

Pamela L. Mellon

Molecular Genetics of Neuroendocrine Control

Mark Mercola

Cardiomyocyte regeneration from stem cells

Andrew Mizisin

ASSESSING THE IMPACT OF OXIDATIVE STRESS ON STRUCUTRAL NERVE INJURY IN DIABETES

Alexandra C. Newton

Effect of Driver Mutations in Cancer on Protein Kinase C Function

Victor Nizet

Interactions of Leading Bacterial Pathogens with the Host Innate Immune System

Peter Novick

Molecular mechanisms of vesicular traffic and organelle inheritance

Daniel O'Connor

Hypertension and chromaffin cell

Karen Oegema

Mechanisms of Cell Division

Robert Oshima

Breast Cancer

Ana Pajor

Sodium-dependent transporters for TCA cycle intermediates

Elena Pasquale

Regulation of gene expression by neuron-glia communication through EphA4 and ephrin-A3

Maurizio Pellechia

Design, synthesis and in vivo characterization of pharmacologically active agents.

James Quigley

Investigating the Role of inflammatory Cells in Tumor Angiogenesis and Tumor Cell Dissemination

Tariq Rana

Architecture and function of molecular assemblies involved in RNAi and HIV replication

Eyal Raz

The impact of intestinal microbiota on intestinal tumorigenesis.

Douglas D. Richman

Natural history and molecular pathogenesis of HIV

Robert Rickert

Molecular mechanisms controlling normal and aberrant B lymphocyte differentiation

Michael Geoff Rosenfeld

Epigenetic, Architectural, and Transcriptome Strategies of Regulated Gene Expression Programs

Guy Salvesen

Proteolytic Signaling

Maike Sander

Differentiation and function of insulin-producing beta cells in the pancreas

Geert Schmid-Schoenbein

The Autodigestion Hypothesis and Inflammation

Gregg Silverman

Inflammation and Apoptosis

Deborah H. Spector

human cytomegalovirus and herpes simplex virus type 2

Stephen A. Spector

HIV, autophagy and Mycobacterial infections

JoAnn Trejo

Protease-activated Receptor Signaling in Vascular Biology and Cancer

Robert H. Tukey

Accessing the metabolic basis of hyperbilirubinemia (jaundice) and CNS toxicity in an animal mode

Ajit P. Varki

Molecular Cell Biology of Sialic Acids

Francisco Javier Villarreal

Effects of cocoa flavanols on muscle performance and mitochondrial function

Miles F. Wilkinson

transcriptional and RNA regulatory mechanisms impacting mammalian fertility, neurological function, and cancer

Dong-Er Zhang

AML1 and AML1-ETO in Hematopoiesis and Leukemogenesis

Kang Zhang

2 Projects in ophthalmology

Binhai Zheng

Axon regeneration and spinal cord repair

Huilin Zhou

DNA Damage Responses
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