Research Interests:
The Microcirculation laboratory is focused on analysis of cardiovascular disease by molecular analysis of inflammatory mechanisms. We have formulated and investigate a new hypothesis for the origin of inflammation, cell and organ failure due to
"auto-digestion".
The current mission is to examine:
- mechanisms that lead to self-digestion by pancreatic enzymes,
- interventions against auto-digestion.
In addition we study alternative trigger mechanisms for inflammation
- the molecular control of cell activation by fluid shear stress,
- the genetic mechanisms for microvascular inflammation in arterial hypertension
- the biomechanical mechanisms for lymph pumping and dysfunction of the primary valve system in the initial lymphatics as source for inflammation.
Track(s):
Physiology
MCB
BMS Focus Areas:
Bioinformatics
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