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Human B cell physiology with emphasis on B cell antigen presentation, accessory molecules involved in cognate T-cell <-> B-cell interactions, signal transduction, and immunoglobulin gene expression; (Human B cell lymphoproliferative diseases with emphasis on pathogenic mechanisms, immunoglobulin gene expression, and innovative forms of immunotherapy; In vitro or in vivo somatic cell transfection or transduction using plasmid DNA or viral expression vectors for gene immunotherapy of neoplastic disease; and Structure-function studies of immunoglobulin or accessory molecules involved in signal transduction or cognate cell-cell interactions.

Track(s):
Microbiology/Immunology


BMS Focus Areas:
Cancer Biology