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My laboratory is interested in understanding the molecular mechanisms of organelle and vesicle movement and the role of transport dysfunction in neurodegenerative diseases. Our focus is on the attachment, function, and regulation of kinesin and dynein microtubule motor proteins. We use molecular and classical genetics, cell biology, and biochemistry in D. melanogaster and M. musculus to make mutants and infer function by phenotypic analysis.

Track(s):
MCB
Genetics

BMS Focus Areas:
Neurobiology