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Lipoprotein metabolism with emphasis on understanding the mechanisms by which lipoproteins participate in the atherogenic process. Current interests focus on the role of oxidized LDL. Studies are underway to determine the mechanisms by which LDL is oxidized in vivo and use techniques of cellular and molecular biology and generation of transgenic models. My lab also demonstrated that oxidation of LDL renders it immunogenic and we are studying the consequences of the immunological response for atherogenesis.

Track(s):
Microbiology/Immunology


BMS Focus Areas:
Endocrinology