Photo of Alexandra C. Newton

Alexandra C. Newton

Professor of Pharmacology
Ph.D., Stanford University

Research Interests:

Our lab investigates the molecular and cellular mechanisms of signal propagation and signal termination in the PI3 kinase and diacylglycerol signaling pathways, and how disruption of these mechanisms results in pathophysiologies.  Specifically, we are interested in how deregulation drives cancer, where signal propagation is upregulated, and degenerative diseases like Alzheimer's, were signal termination is upregulated.    We focus, in particular, on protein kinase C and the phosphatase our lab discovered, PHLPP.  Deregulated activity of either causes pathophysiologies.


Molecular Pharmacology


BMS Focus Areas:

Cancer Biology

Structural Chemical Biology

Selected Publications:

Web Page: